{"created":"2023-06-20T15:01:37.474214+00:00","id":1178,"links":{},"metadata":{"_buckets":{"deposit":"5c9e1263-45b0-4d48-aca0-0f974a85fd65"},"_deposit":{"created_by":10,"id":"1178","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"1178"},"status":"published"},"_oai":{"id":"oai:kdu.repo.nii.ac.jp:00001178","sets":["77:105:107"]},"author_link":["3529","63"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-12-30","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-2","bibliographicPageEnd":"73","bibliographicPageStart":"69","bibliographicVolumeNumber":"53","bibliographic_titles":[{"bibliographic_title":"神奈川歯学","bibliographic_titleLang":"ja"},{"bibliographic_title":"The Journal of the Kanagawa Odontological Society","bibliographic_titleLang":"en"}]}]},"item_10001_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"バイオフィルム形成において重要な働きが認められ、歯周炎の進行に関与すると考えられているActinomyces naeslundiiの培養温度や栄養源となる培地組成の違いによる増殖速度やバイオフィルム形成について評価した。さらに、A.naeslundiiの口腔内定着因子とされている菌体表層の構造物である線毛タンパク質発現への影響について検討した。37℃と39℃で比較した結果、A.naeslundii菌体の発育に大きな変化は認められなかったが、栄養源となる培地濃度の低下により増殖が抑制されていた。37℃に比べて39℃で培養した時ではバイオフィルム形成細菌数が半減し、培地濃度に依存的なバイオフィルムの形成が認められた。また、菌体タンパク質の発現量は37℃に比べて39℃培養時に減少し、培地濃度に依存してタンパク質の減少が認められた。","subitem_description_type":"Abstract"}]},"item_10001_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.18924/00001141","subitem_identifier_reg_type":"JaLC"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"神奈川歯科大学学会","subitem_publisher_language":"ja"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00043576","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0454-8302","subitem_source_identifier_type":"PISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"佐藤, 武則","creatorNameLang":"ja"},{"creatorName":"サトウ, タケノリ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"3529","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sato, Takenori","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"63","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-09-06"}],"displaytype":"detail","filename":"53(1-2)_69-73_fulltext.pdf","filesize":[{"value":"2.4 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"Full Text（全文）","url":"https://kdu.repo.nii.ac.jp/record/1178/files/53(1-2)_69-73_fulltext.pdf"},"version_id":"da7ab5ea-0fd2-432b-9421-06620a782c83"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Actinomyces naeslundii","subitem_subject_scheme":"Other"},{"subitem_subject":"口腔バイオフィルム","subitem_subject_scheme":"Other"},{"subitem_subject":"線毛","subitem_subject_scheme":"Other"},{"subitem_subject":"歯周炎","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Actinomyces naeslundii線毛による口腔バイオフィルム形成機構の解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Actinomyces naeslundii線毛による口腔バイオフィルム形成機構の解明","subitem_title_language":"ja"}]},"item_type_id":"10001","owner":"10","path":["107"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-09-06"},"publish_date":"2019-09-06","publish_status":"0","recid":"1178","relation_version_is_last":true,"title":["Actinomyces naeslundii線毛による口腔バイオフィルム形成機構の解明"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2023-11-30T07:23:46.824949+00:00"}