{"created":"2023-06-20T15:01:22.559495+00:00","id":914,"links":{},"metadata":{"_buckets":{"deposit":"38706a34-ce0c-4e2f-a717-8c0fe5fc5418"},"_deposit":{"created_by":10,"id":"914","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"914"},"status":"published"},"_oai":{"id":"oai:kdu.repo.nii.ac.jp:00000914","sets":["6:9"]},"author_link":["2397","2464"],"item_10006_date_granted_11":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2014-03-17"}]},"item_10006_degree_grantor_9":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_name":"神奈川歯科大学"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"32703","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_10006_degree_name_8":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（歯学）"}]},"item_10006_description_10":{"attribute_name":"学位授与年度","attribute_value_mlt":[{"subitem_description":"2013","subitem_description_type":"Other"}]},"item_10006_description_17":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_10006_description_7":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"石灰化分化誘導培地(ODM)を用いて作製したECM含有βリン酸三カルシウム(β-TCP)がラット骨髄間葉系幹細胞(BMSC)に与える影響について検討した。ODMで1、2週間の培養を行い、I群、II群のヒト歯槽骨骨膜由来細胞(HABPC)/β-TCP)とした。I群の表層には多くのHABPCの伸展が観られたが、深部の小孔内では小孔壁表面にのみわずかに伸展した。II群では、I群に比較して深部の小孔内全体にHABPCが有意に多く伸展した。BMSC/β-TCP-ECMでは、対照と比較してI、II群で有意に多くの細胞がβ-TCP表層の小孔内に進展した。HABPC/β-TCPでは、ALP、Col-I、Runx2、オステオカルシン(OC)、オステオポンチン(OP)の全ての陽性反応は、I群よりII群で多く認めた。BMSC/β-TCP-ECMでは、Ki-67陽性反応は、I群、II群は対照より有意に多く認めた。","subitem_description_type":"Abstract"}]},"item_10006_dissertation_number_12":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"乙第488号"}]},"item_10006_heading_21":{"attribute_name":"見出し","attribute_value_mlt":[{"subitem_heading_headline":"PDF/A","subitem_heading_language":"ja"}]},"item_10006_relation_14":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"神奈川歯学, 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Type I","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"Core Binding Factor Alpha 1 Subunit","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"*間葉系間質細胞","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"*Beta-Tricalcium Phosphate","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"ヒト","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"ラット","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"動物","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"中年(45〜64)","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"オス","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"歯学","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral 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