{"created":"2023-06-20T15:01:23.888496+00:00","id":945,"links":{},"metadata":{"_buckets":{"deposit":"e6be4acf-62e1-4e7b-a5ce-45018ca6e729"},"_deposit":{"created_by":10,"id":"945","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"945"},"status":"published"},"_oai":{"id":"oai:kdu.repo.nii.ac.jp:00000945","sets":["6:7"]},"author_link":["2526","2527"],"item_10006_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"歯科用レジン照射器による青色光は摘出ラット大動脈に対して光誘導性血管収縮を誘導す","subitem_alternative_title_language":"ja"}]},"item_10006_date_granted_11":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2016-03-17"}]},"item_10006_degree_grantor_9":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_name":"神奈川歯科大学"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"32703","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_10006_degree_name_8":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（臨床歯学）"}]},"item_10006_description_10":{"attribute_name":"学位授与年度","attribute_value_mlt":[{"subitem_description":"2015","subitem_description_type":"Other"}]},"item_10006_description_17":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_10006_description_7":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Aims: Currently, the blue light of resin curing unit is frequently used in dental treatment. However, the influence of the blue light irradiation on oral tissue is not  lear. The aim of this study was to elucidate the effect of dental blue light irradiation on vascular smooth muscle.\nMethods: Isolated rat descending aorta was suspended in a superfusion chamber  nd superfused continuously with Krebs-Ringer solution. The changes in isometric  orce of blue light irradiation were assessed using vessel strips superfused with the Krebs-Ringer solution alone or the Krebs-Ringer solutions containing 10 µM  hentolamine, 100 mM dimethyl sulfoxide, 10 unit/mL superoxide dismutase, or 5  M L-histidine. The reactive oxygen species (ROS) scavenging activity of antioxidants was examined using the electron spin resonance technique  espectively.\nResults: We first demonstrated that the vasoconstriction was induced by irradiated of blue light using dental resin curing unit. The vasoconstriction was inhibited by  ncluding in the Krebs-Ringer solution an α-receptor blocker that inhibits the  eurotransmitter. This phenomenon was controlled with the addition of ROS  cavengers.\nConclusions: Blue light irradiation of multiple times in dental treatment might have the potential to accelerate aging of pulpal blood vessel from ischemia through dental pulp vasoconstriction via ROS generation. In addition, prolonged and/or repeated blue light irradiation could cause ROS-induced oxidative stress such as ischemia-reperfusion injury on pulpal blood vessel. Therefore, preintake of  ntioxidants is suggested to avoid effects such as aging of dental pulp due to blue light irradiation-induced ROS in dental clinic treatments.","subitem_description_type":"Abstract"}]},"item_10006_dissertation_number_12":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第479号"}]},"item_10006_heading_21":{"attribute_name":"見出し","attribute_value_mlt":[{"subitem_heading_headline":"PDF/A","subitem_heading_language":"ja"}]},"item_10006_relation_14":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Oral Health and Dental Management, 13(4):1147-1151, 2014. doi: 10.4172/2247-2452.1000745"}]}]},"item_10006_relation_15":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"OMICS"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.omicsonline.org/archive/ohdm-volume-13-issue-4-year-2014.html","subitem_relation_type_select":"URI"}}]},"item_10006_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"岩田, 将","creatorNameLang":"ja"},{"creatorName":"イワタ, ショウ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2526","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Iwata, Sho","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2527","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-20"}],"displaytype":"detail","filename":"kou479_fulltext.pdf","filesize":[{"value":"987.7 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"Full Text（全文）","objectType":"fulltext","url":"https://kdu.repo.nii.ac.jp/record/945/files/kou479_fulltext.pdf"},"version_id":"57a6f25e-30a6-4cbb-b99b-698f80007035"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-07-05"}],"displaytype":"detail","filename":"kou479_summary.pdf","filesize":[{"value":"243.0 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"論文内容要旨","url":"https://kdu.repo.nii.ac.jp/record/945/files/kou479_summary.pdf"},"version_id":"fa8cb4ef-9035-4a21-9414-d50e94f8e5a9"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-07-05"}],"displaytype":"detail","filename":"kou479_thesisreview.pdf","filesize":[{"value":"193.4 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"論文審査要旨、最終審査の結果の要旨","url":"https://kdu.repo.nii.ac.jp/record/945/files/kou479_thesisreview.pdf"},"version_id":"c98fa69e-3ed7-40e0-894d-a6158364730d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Reactive oxygen species","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Dental curing lights","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Vasoconstriction","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Antioxidant","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Blue Light from Dental Resin Curing Unit Causes Light-Induced Vasoconstriction in Isolated Rat Aorta","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Blue Light from Dental Resin Curing Unit Causes Light-Induced Vasoconstriction in Isolated Rat Aorta","subitem_title_language":"en"}]},"item_type_id":"10006","owner":"10","path":["7"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2016-07-05"},"publish_date":"2016-07-05","publish_status":"0","recid":"945","relation_version_is_last":true,"title":["Blue Light from Dental Resin Curing Unit Causes Light-Induced Vasoconstriction in Isolated Rat Aorta"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2023-12-21T01:26:39.926913+00:00"}